Zur Xbox 360-Version von Mass Effect 2 wurde ein neuer Patch veröffentlicht, der folgende Verbesserungen bzw. neue Features mitbringt:
[quote]* Scanning for minerals has been optimized
* Fixed an issue with marking all entries as viewed in the Journal
* Fixed an issue relating to text and the menu screen
* Fixed an issue relating to players starting a new game and loading a save
* Fixed multiple issues when loading a save containing DLC when DLC isn't present
* Fixed an issue with ammo flashing when it can't be picked up
* Fixed an issue with crosshairs
* Fixed an issue with Grunt's Fortification power
* Fixed an issue with enemies and cover
* Fixed an issue where players could receive additional talent points
* Fixed an issue where squad members would overwrite ammo powers the player had assigned them[/quote]
Ein entsprechender Patch für die PC-Version befindet bereits in Arbeit.